Effects of Long-Term In Vivo Exposure to Di-2-Ethylhexylphthalate on Thyroid Hormones and the TSH/TSHR Signaling Pathways in Wistar Rats
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چکیده
منابع مشابه
Effects of Long-Term In Vivo Exposure to Di-2-Ethylhexylphthalate on Thyroid Hormones and the TSH/TSHR Signaling Pathways in Wistar Rats
Di-(2-ethylhexyl)phthalate (DEHP) was a widely used chemical with human toxicity. Recent in vivo and in vitro studies suggested that DEHP-exposure may be associated with altered serum thyroid hormones (THs) levels, but the underlying molecular mechanisms were largely unknown. To explore the possible molecular mechanisms, 128 Wistar rats were dosed with DEHP by gavage at 0, 150, 300, and 600 mg/...
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متن کامل
long-term effects of maternal exposure to di (2-ethylhexyl) phthalate on sperm and testicular parameters in wistar rats offspring
background: phthalate esters have been shown to cause reproductive toxicity in both developing and adult animals. objective: this study was designed to assess long-term effects of maternal exposure to di (2-ethylhexyl) phthalate (dehp) on reproductive ability of both neonatal and adult male offspring. materials and methods: 60 female rats randomly divided in four equal groups; vehicle control a...
متن کاملLong-term effects of maternal exposure to Di (2-ethylhexyl) Phthalate on sperm and testicular parameters in Wistar rats offspring
BACKGROUND Phthalate esters have been shown to cause reproductive toxicity in both developing and adult animals. OBJECTIVE This study was designed to assess long-term effects of maternal exposure to Di (2-ethylhexyl) Phthalate (DEHP) on reproductive ability of both neonatal and adult male offspring. MATERIALS AND METHODS 60 female rats randomly divided in four equal groups; vehicle control ...
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ژورنال
عنوان ژورنال: International Journal of Environmental Research and Public Health
سال: 2017
ISSN: 1660-4601
DOI: 10.3390/ijerph14010044